Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma

@inproceedings{Teng2015FucoidanSH,
  title={Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma},
  author={Hongming Teng and Yazong Yang and Hengyun Wei and Zundong Liu and Zhichao Liu and Yanhong Ma and Zixiang Gao and L. Steven Hou and Xiangyang Zou and Paul Long},
  booktitle={Marine drugs},
  year={2015}
}
Metastasis, the greatest clinical challenge associated with cancer, is closely connected to multiple biological processes, including invasion and adhesion. The hypoxic environment in tumors is an important factor that causes tumor metastasis by activating HIF-1α. Fucoidan, extracted from brown algae, is a sulfated polysaccharide and, as a novel marine biological material, has been used to treat various disorders in China, Korea, Japan and other countries. In the present study, we demonstrated… CONTINUE READING
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