Fucogalactan from the giant mushroom Macrocybe titans inhibits melanoma cells migration.

@article{Milhorini2018FucogalactanFT,
  title={Fucogalactan from the giant mushroom Macrocybe titans inhibits melanoma cells migration.},
  author={Shayane da Silva Milhorini and Fhernanda Ribeiro Smiderle and Stellee Marcela Petris Biscaia and F{\'a}bio R. Rosado and Edvaldo da Silva Trindade and Marcello Iacomini},
  journal={Carbohydrate polymers},
  year={2018},
  volume={190},
  pages={
          50-56
        }
}
An aqueous extract containing polysaccharides was obtained from the giant mushroom Macrocybe titans, and it was purified by amylase treatment, freeze-thawing process and dialysis. The purified fraction (ESP) was analyzed by HPSEC and GC-MS which showed a homogenous polysaccharide with Mw 14.2 × 103 g/mol composed by galactose and fucose. NMR and methylation analysis of ESP confirmed the presence of a fucogalactan with a (1 → 6)-linked α-d-Galp main chain partially substituted at O-2 by non… Expand
10 Citations
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An α-D-galactan and a β-D-glucan from the mushroom Amanita muscaria: Structural characterization and antitumor activity against melanoma.
  • Matheus Zavadinack, Daniel de Lima Bellan, +6 authors Marcello Iacomini
  • Medicine, Chemistry
  • Carbohydrate polymers
  • 2021
Polysaccharides α-D-galactan (GAL-Am) and β-D-glucan (GLC-Am) were obtained from Amanita muscaria fruiting bodies. They were purified using different methodologies, such as Fehling precipitation (forExpand

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