Fuc-GM1 ganglioside mimics the receptor function of GM1 for cholera toxin.

@article{Masserini1992FucGM1GM,
  title={Fuc-GM1 ganglioside mimics the receptor function of GM1 for cholera toxin.},
  author={Massimo Masserini and Ernesto Freire and Paola Palestini and E. Calappi and Guido Tettamanti},
  journal={Biochemistry},
  year={1992},
  volume={31 8},
  pages={2422-6}
}
The ability of Fuc-GM1 ganglioside to mimic the receptor function of GM1 for cholera toxin (CT) has been investigated. For this purpose, rat glioma C6 cultured cells were enriched with Fuc-GM1 and the responsiveness to CT was compared with that of cells enriched with GM1 ganglioside. Fuc-GM1 was taken up by cells as rapidly and to the same extent as GM1. When comparable amounts of ganglioside were associated, the cells enriched with Fuc-GM1 bound the same amount of 125I-CT as did cells enriched… CONTINUE READING

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