FtsH cleavage of non-native conformations of proteins.

Abstract

FtsH is a peculiar prokaryotic protease with low unfoldase activity. Different reports have proposed that FtsH substrates could be either tagged proteins or proteins of low stability. We show here that FtsH degradation of 31 point mutants of Anabaena apoflavodoxin is inversely proportional to their conformational stabilities, and that the same applies to… (More)
DOI: 10.1016/j.jsb.2010.05.001

Topics

  • Presentations referencing similar topics