Fruit bats as reservoirs of Ebola virus

  title={Fruit bats as reservoirs of Ebola virus},
  author={Eric M. Leroy and Brice Serge Kumulungui and Xavier Pourrut and Pierre Rouquet and Alexandre Hassanin and Philippe Yaba and Andr{\'e} D{\'e}licat and Janusz T. Pawęska and Jean Paul Gonzalez and Robert Swanepoel},
The first recorded human outbreak of Ebola virus was in 1976, but the wild reservoir of this virus is still unknown. Here we test for Ebola in more than a thousand small vertebrates that were collected during Ebola outbreaks in humans and great apes between 2001 and 2003 in Gabon and the Republic of the Congo. We find evidence of asymptomatic infection by Ebola virus in three species of fruit bat, indicating that these animals may be acting as a reservoir for this deadly virus. 
Fruit Bats Serve as Ebola Reservoir
Investigators have tested for Ebola virus in 1030 animals trapped during three excursions to areas of Gabon and the Republic of Congo, finding no evidence of the virus in these animals.
Evolutionary history of Ebola virus
A hypothesis of the evolutionary history of Ebola virus is proposed which will be helpful to investigate the molecular evolution of these viruses.
Ebola Virus Antibodies in Fruit Bats, Bangladesh
These bats might be a reservoir for Ebola or Ebola-like viruses, and extend the range of filoviruses to mainland Asia.
Filoviruses and bats.
Ecological investigations following Marburg virus disease outbreaks associated with entry into caves inhabited by Rousettus aegyptiacus bats led to the identification of this bat species as the natural reservoir host of the marburgviruses.
Ebolavirus and Other Filoviruses
Animal trapping missions were carried out in the Central African rain forest in an area where several epidemics and epizootics had occurred between 2001 and 2005 and three species of fruit bats were found asymptomatically and naturally infected with Ebola virus.
Investigating the zoonotic origin of the West African Ebola epidemic
The range of possible Ebola virus sources is expanded to include insectivorous bats and the importance of broader sampling efforts for understanding Ebola virus ecology is reiterated.
Discovery of an Ebolavirus-Like Filovirus in Europe
Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and
The ecology of Ebola virus.


The natural history of Ebola virus in Africa.
Multiple Ebola Virus Transmission Events and Rapid Decline of Central African Wildlife
Recovered carcasses were infected by a variety of Ebola strains, suggesting that Ebola outbreaks in great apes result from multiple virus introductions from the natural host.
Experimental inoculation of plants and animals with Ebola virus.
Thirty-three varieties of 24 species of plants and 19 species of vertebrates and invertebrates were experimentally inoculated with Ebola Zaire virus and died; deaths occurred only among bats that had not adapted to the diet fed in the laboratory.
Isolation of Hendra virus from pteropid bats: a natural reservoir of Hendra virus.
The isolation of HeV from pteropid bats corroborates earlier serological and epidemiological evidence that they are a natural reservoir host of the virus and reinforces the hypothesis that HeV excretion from bats might be related to the birthing process.
Serologic Evidence of Lyssavirus Infections among Bats, the Philippines
Results from the virus neutralization assays are consistent with the presence in the Philippines of a naturally occurring Lyssavirus related to ABLV.
Catastrophic ape decline in western equatorial Africa
Survey results conservatively indicate that ape populations in Gabon declined by more than half between 1983 and 2000, and gorillas and common chimpanzees should be elevated immediately to ‘critically endangered’ status.
Sequence analysis of the Marburg virus nucleoprotein gene: comparison to Ebola virus and other non-segmented negative-strand RNA viruses.
Alignments of the entire NP amino acid sequences of these viruses also suggest that filoviruses are more closely related to paramyxovirus than to rhabdovirus genera.
Taxonomy and biogeography of African fruit bats (Mammalia, Megachiroptera). 2. The genera Micropteropus Matschie, 1899, Epomops Gray, 1870, Hypsignathus H. Allen, 1861, Nanonycteris Matschie, 1899, and Plerotes Andersen, 1910
The skull characters traditionally used to distinguish Micropteropus from Epomophorus Bennett, 1836 are found to be rather in line with the tendencies in that genus, and certain wing characters claimed to distinguish it are rejected and the need for wet preservation of future specimens is emphasized.