Fructus agni casti and bromocriptine for treatment of hyperprolactinemia and mastalgia

  title={Fructus agni casti and bromocriptine for treatment of hyperprolactinemia and mastalgia},
  author={Esra Bulgan Kılıçdağ and Ebru Tarım and Tayfun Bağış and Serkan Erkanli and E. Aslan and Kursat Ozsahin and Esra Kuşçu},
  journal={International Journal of Gynecology \& Obstetrics},
Hyperprolactinemia is the most common endocrine disorder of the hypothalamic–pituitary axis w1x. Research has proven that there is a causal connection between latent hyperprolactinemia and mastalgia w2x. The aim of this study was to investigate fructus agni casti as treatment for mild hyperprolactinemia and for mastalgia, and to compare its efficacy with that of bromocriptine (dopamine agonist ) therapy. This prospective study involved 40 women with cyclic mastalgia (Group 1) and 40 with mild… 
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This study provides the documentation for scientists to use the properties of V. agnus-castus as an effective herbal medicine and its safety and acceptable dosage are discussed.
Vitex agnus castus might enrich the pharmacological armamentarium for medical treatment of prolactinoma Dear Editor, Gallagher et al. have recently reported the interesting case of a patient with an undiagnosed prolactinoma who had improved symptoms of hyperprolactinemia following administration of
[2] Sciscione A, Ivester T, Largoza M, Manley J, Shlossman P, Colmorgen GHC. Acute pulmonary edema in pregnancy. Obstet Gynecol 2003;101:511–5. [3] Eisenhut M. Comment on ‘‘risk factors for acute
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Herbal medicine for the treatment of oligo / amenorrhoea , hyperandrogenism and polycystic ovary syndrome ( PCOS ) ; a review of the laboratory and clinical evidence
  • 2014
Polycystic ovary syndrome PCOS is a common reproductive and endocrine disorder affecting up to 17.8% of reproductive aged women [1]. It is a life-long condition and although the exact cause is yet to
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Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L.) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial
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Vitex agnus castus extract BNO 1095 shows effective in treating moderate to severe PMS in Chinese women, especially in symptoms of negative affect and water retention.


Hyperprolactinemia: etiology, diagnosis, and management.
The goals of treatment are to normalize prolactin levels, restore gonadal function, and reduce the effects of chronic hyperprolactinemia, and dopamine agonists are the treatment of choice for the majority of patients.
Guidelines for the diagnosis and treatment of hyperprolactinemia.
Results of comparative studies indicate that cabergoline is clearly superior to bromocriptine in efficacy (PRL suppression, restoration of gonadal function) and tolerability.
Serum Prolactin Levels in Patients With Fibrocystic Breast Disease
Results indicate that a high proportion of patients with fibrocystic breast disease exhibit increased daily prolactin secretion, and the response to TRH stimulation was significantly higher in the study patients than in the controls.
Heterogeneous distribution of serum prolactin values in apparently healthy young women, and the effects of oral contraceptive medication.
Controversy over effects of oral contraceptives (OCs) on serum prolactin (PRL) levels from retrospective studies suggested performing a prospective study. Statistical analyses of PRL levels in 552