Fructose overfeeding in first-degree relatives of type 2 diabetic patients impacts energy metabolism and mitochondrial functions in skeletal muscle.

Abstract

SCOPE The aim of the study was to assess the effects of a high-fructose diet (HFrD) on skeletal muscle transcriptomic response in healthy offspring of patients with type 2 diabetes, a subgroup of individuals prone to metabolic disorders. METHODS AND RESULTS Ten healthy normal weight first-degree relatives of type 2 diabetic patients were submitted to a… (More)
DOI: 10.1002/mnfr.201600407

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