Fructose‐2,6‐bisphosphate and control of carbohydrate metabolism in eukaryotes

@article{Okar1999Fructose26bisphosphateAC,
  title={Fructose‐2,6‐bisphosphate and control of carbohydrate metabolism in eukaryotes},
  author={David A. Okar and Alex J. Lange},
  journal={BioFactors},
  year={1999},
  volume={10}
}
Fructose‐2,6‐bisphosphate is an important intracellular biofactor in the control of carbohydrate metabolic fluxes in eukaryotes. It is generated from ATP and fructose‐6‐phosphate by 6‐phosphofructo‐2‐kinase and degraded to fructose‐6‐phosphate and phosphate ion by fructose‐2,6‐bisphosphatase. In most organisms these enzymatic activities are contained in a single polypeptide. The reciprocal modulation of the kinase and bisphosphatase activities by post‐translational modifications places the… 

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  • J. Chesney
  • Biology
    Current opinion in clinical nutrition and metabolic care
  • 2006
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