Frontotemporal neural systems in bipolar disorder.

  title={Frontotemporal neural systems in bipolar disorder.},
  author={Hilary Patricia Blumberg and Dennis S. Charney and John H. Krystal},
  journal={Seminars in clinical neuropsychiatry},
  volume={7 4},
Relatively less research has been performed in the delineation of the neural system abnormalities underlying bipolar disorder (BD) than in their correlates in unipolar depression. However, neuroimaging research has recently provided in vivo evidence to support the involvement of regional brain abnormalities in BD implicated by the localization of lesions associated with secondary mood symptoms. This article reviews (1) neural systems implicated in BD by brain lesions associated with secondary… CONTINUE READING

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