Frontotemporal dementia with co-occurrence of astrocytic plaques and tufted astrocytes, and severe degeneration of the cerebral white matter: a variant of corticobasal degeneration?

@article{Tan2004FrontotemporalDW,
  title={Frontotemporal dementia with co-occurrence of astrocytic plaques and tufted astrocytes, and severe degeneration of the cerebral white matter: a variant of corticobasal degeneration?},
  author={Chun-Feng Tan and Yue-Shan Piao and Akiyoshi Kakita and Mitsunori Yamada and Hiroki Takano and Masaharu Tanaka and Atsushi Mano and Kunihiko Makino and Masatoyo Nishizawa and Koichi Wakabayashi and Hitoshi Takahashi},
  journal={Acta Neuropathologica},
  year={2004},
  volume={109},
  pages={329-338}
}
We report two patients who exhibited frontotemporal dementia (FTD) with unusual neuropathological features. The ages of the patients at death were 65 and 67 years, the disease durations were 6 and 5 years, and the clinical diagnoses were Pick’s disease and corticobasal degeneration (CBD), respectively. At autopsy, both cases exhibited neuropathological findings compatible with those of CBD, including atrophy of the frontal and parietal lobes, neuronal loss and gliosis in the cortical and… CONTINUE READING

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