Fronto-limbic novelty processing in acute psychosis: disrupted relationship with memory performance and potential implications for delusions

Abstract

Recent concepts have highlighted the role of the hippocampus and adjacent medial temporal lobe (MTL) in positive symptoms like delusions in schizophrenia. In healthy individuals, the MTL is critically involved in the detection and encoding of novel information. Here, we aimed to investigate whether dysfunctional novelty processing by the MTL might… (More)
DOI: 10.3389/fnbeh.2015.00144

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