Fronto-limbic function in unaffected offspring at familial risk for bipolar disorder during an emotional working memory paradigm

@article{Ladouceur2013FrontolimbicFI,
  title={Fronto-limbic function in unaffected offspring at familial risk for bipolar disorder during an emotional working memory paradigm},
  author={Cecile D. Ladouceur and Vaibhav A. Diwadkar and Richard E. White and Jeremy Bass and Boris J Birmaher and David Axelson and Mary L. Phillips},
  journal={Developmental Cognitive Neuroscience},
  year={2013},
  volume={5},
  pages={185-196}
}
Evidence from neuroimaging studies indicate that individuals with bipolar disorder (BD) exhibit altered functioning of fronto-limbic systems implicated in voluntary emotion regulation. Few studies, however, have examined the extent to which unaffected youth at familial risk for BD exhibit such alterations. Using an fMRI emotional working memory paradigm, we investigated the functioning of fronto-limbic systems in fifteen healthy bipolar offspring (8-17 years old) with at least one parent… CONTINUE READING
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