Fronto-limbic disconnection in bipolar disorder.

@article{Radaelli2015FrontolimbicDI,
  title={Fronto-limbic disconnection in bipolar disorder.},
  author={Daniele Radaelli and Giovanna Sferrazza Papa and Benedetta Vai and Sara Poletti and Enrico Smeraldi and Cristina Colombo and Francesco Benedetti},
  journal={European psychiatry : the journal of the Association of European Psychiatrists},
  year={2015},
  volume={30 1},
  pages={82-8}
}
BACKGROUND Bipolar disorder (BD) is a severe, disabling and life-threatening illness. Disturbances in emotion and affective processing are core features of the disorder with affective instability being paralleled by mood-congruent biases in information processing that influence evaluative processes and social judgment. Several lines of evidence, coming from neuropsychological and imaging studies, suggest that disrupted neural connectivity could play a role in the mechanistic explanation of… CONTINUE READING
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