Frontline: Inhibition of allergen‐induced pulmonary inflammation by the tripeptide feG: a mimetic of a neuro‐endocrine pathway

@article{Dry2004FrontlineIO,
  title={Frontline: Inhibition of allergen‐induced pulmonary inflammation by the tripeptide feG: a mimetic of a neuro‐endocrine pathway},
  author={R. D{\'e}ry and M. Ulanova and L. Puttagunta and G. Stenton and D. James and S. Merani and R. Mathison and J. Davison and A. Befus},
  journal={European Journal of Immunology},
  year={2004},
  volume={34}
}
  • R. Déry, M. Ulanova, +6 authors A. Befus
  • Published 2004
  • Medicine
  • European Journal of Immunology
  • Interactions between the neuro‐endocrine system and immune system help maintain health. One interaction involves the superior cervical ganglia (SCG), which regulate the prohormone submandibular rat 1 (SMR1) produced by the submandibular gland (SMG). A peptide derived from SMR1, feG, has anti‐inflammatory activity, and modification to D‐isomer feG enhances bioactivity. We tested feG as a therapeutic agent for airways inflammation, using rats sensitized by OVA or Nippostrongylus brasiliensis (Nb… CONTINUE READING
    36 Citations
    The tripeptide feG regulates the production of intracellular reactive oxygen species by neutrophils
    • 13
    feG-COOH blunts eosinophilic airway inflammation in a feline model of allergic asthma
    • 12
    Chronic use of the immunomodulating tripeptide feG-COOH in experimental feline asthma.
    • 16
    • Highly Influenced
    Effects of the recombinant allergen rDer f 2 on neuro-endocrino-immune network in asthmatic mice
    • 3
    • PDF
    Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects
    • 29
    • PDF
    The tripeptide analog feG ameliorates severity of acute pancreatitis in a caerulein mouse model.
    • 23
    • PDF

    References

    SHOWING 1-10 OF 38 REFERENCES
    Marked antiinflammatory effects of decentralization of the superior cervical ganglia
    • 44
    • PDF
    Regulation of leukocyte adhesion to heart by the tripeptides feG and feG(NH2).
    • 18
    Submandibular Gland Peptide-T (SGP-T) Inhibits Intestinal Anaphylaxis
    • 11