Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm.

  title={Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm.},
  author={Boubacar Benziane and Alexander V. Chibalin},
  journal={American journal of physiology. Endocrinology and metabolism},
  volume={295 3},
  • B. Benziane, A. Chibalin
  • Published 1 September 2008
  • Biology
  • American journal of physiology. Endocrinology and metabolism
The skeletal muscle sodium pump plays a major role in the removal of K(+) ions from the circulation postprandial, or after a physical activity bout, thereby preventing the development of hyperkalemia and fatigue. Insulin and muscle contractions stimulate Na(+)-K(+)-ATPase activity in skeletal muscle, at least partially via translocation of sodium pump units to the plasma membrane from intracellular stores. The molecular mechanism of this phenomenon is poorly understood. Due to the contradictory… 

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