Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia.

@article{Seeley2008FrontalPN,
  title={Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia.},
  author={William W. Seeley and Richard Crawford and Katya Rascovsky and Joel H. Kramer and Michael Weiner and Bruce L. Miller and Maria Luisa Gorno-Tempini},
  journal={Archives of neurology},
  year={2008},
  volume={65 2},
  pages={
          249-55
        }
}
BACKGROUND Behavioral variant frontotemporal dementia (bvFTD) strikes hardest at the frontal lobes, but the sites of earliest injury remain unclear. OBJECTIVE To determine atrophy patterns in distinct clinical stages of bvFTD, testing the hypothesis that the mildest stage is restricted to frontal paralimbic cortex. DESIGN A bvFTD cohort study. SETTING University hospital dementia clinic. PARTICIPANTS Patients with bvFTD with Clinical Dementia Rating (CDR) scale scores of 0.5 (n = 15), 1… CONTINUE READING
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