Frontal cortex lesions eliminate the clock speed effect of dopaminergic drugs on interval timing.

@article{Meck2006FrontalCL,
  title={Frontal cortex lesions eliminate the clock speed effect of dopaminergic drugs on interval timing.},
  author={Warren H. Meck},
  journal={Brain research},
  year={2006},
  volume={1108 1},
  pages={157-67}
}
Behavioral and pharmacological challenges using methamphetamine (MAP-0.5 and 1.0 mg/kg, i.p.), haloperidol (HAL-0.12 mg/kg, i.p.), and sulfated cholecystokinin octapeptide (CCK-0.05 and 0.1 mg/kg, i.p.) were used to evaluate the effects of excitotoxic lesions of cholinergic cell bodies in the medial septal area and the nucleus basalis magnocellularis, radiofrequency lesions of the fimbria-fornix, and aspiration lesions of the frontal cortex on interval timing in rats trained on a 40-s peak… CONTINUE READING
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