Frontal FDG-PET activity correlates with cognitive outcome after STN-DBS in Parkinson disease.

@article{Kalbe2009FrontalFA,
  title={Frontal FDG-PET activity correlates with cognitive outcome after STN-DBS in Parkinson disease.},
  author={Elke Kalbe and J{\"u}rgen Voges and Thomas Weber and M Haarer and Simon Baudrexel and Johannes C. Klein and Josef Kessler and Volker J{\"o}rg Friedrich Sturm and W-D Heiss and R{\"u}diger Hilker},
  journal={Neurology},
  year={2009},
  volume={72 1},
  pages={42-9}
}
BACKGROUND Inconsistent changes of cognitive functioning have been reported in patients with Parkinson disease (PD) with deep brain stimulation (DBS) of the subthalamic nucleus (STN). To investigate the underlying pathomechanisms, we correlated alterations of cognitive test performance and changes of neuronal energy metabolism in frontal basal ganglia projection areas under bilateral STN stimulation. METHODS We conducted verbal fluency, learning, and memory tests and 18-fluorodeoxyglucose… CONTINUE READING

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