Frondoside A potentiates the effects of conventional therapeutic agents in acute leukemia.

@article{Sajwani2017FrondosideAP,
  title={Frondoside A potentiates the effects of conventional therapeutic agents in acute leukemia.},
  author={F H Sajwani and Peter D. Collin and Thomas Edward Adrian},
  journal={Leukemia research},
  year={2017},
  volume={63},
  pages={98-108}
}
Acute leukemia is the major cause of mortality in hematological malignancies. Despite improvement of survival with current chemotherapies, patients die from the disease or side-effects of treatment. Thus, new therapeutic agents are needed. Frondoside A is a triterpenoid glycoside originally isolated from the sea cucumber, Cucumaria frondosa that has potent antitumor effects in various cancers. The current study investigated the effects of frondoside A in acute leukemia cell lines alone and in… CONTINUE READING
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