From ugly fish to conquer death: J J R Macleod's fish insulin research, 1922–24

@article{Wright2002FromUF,
  title={From ugly fish to conquer death: J J R Macleod's fish insulin research, 1922–24},
  author={James R. Wright},
  journal={The Lancet},
  year={2002},
  volume={359},
  pages={1238-1242}
}
Fish insulin research had a very short heyday. Throughout most of 1922, production of insulin from livestock was difficult, erratic, and expensive. Although fish insulin was easy to extract and seemed to be a brilliant and logical solution to the shortage of insulin, collection of fish islets was a logistical nightmare. By the end of 1922, a scientist at the pharmaceutical company Eli Lilly in Indianapolis, IN, USA had developed a way to concentrate and purify insulin by isoelectric… Expand

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