From the archives of the AFIP. Radiologic spectrum of Paget disease of bone and its complications with pathologic correlation.

@article{Smith2002FromTA,
  title={From the archives of the AFIP. Radiologic spectrum of Paget disease of bone and its complications with pathologic correlation.},
  author={Stacy E. Smith and Mark D. Murphey and Kambiz Motamedi and Michael E. Mulligan and Charles S. Resnik and Francis H. Gannon},
  journal={Radiographics : a review publication of the Radiological Society of North America, Inc},
  year={2002},
  volume={22 5},
  pages={1191-216}
}
Paget disease of bone is a common disorder affecting approximately 3%-4% of the population over 40 years of age. The pathologic abnormality in Paget disease is excessive and abnormal remodeling of bone. Three pathologic phases have been described: the lytic phase (incipient-active), in which osteoclasts predominate; the mixed phase (active), in which osteoblasts cause repair superimposed on the resorption; and the blastic phase (late-inactive) in which osteoblasts predominate. Radiographic… CONTINUE READING
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