From the Cover: Zinc Deficiency Worsens and Supplementation Prevents High-Fat Diet Induced Vascular Inflammation, Oxidative Stress, and Pathological Remodeling.

@article{Chen2016FromTC,
  title={From the Cover: Zinc Deficiency Worsens and Supplementation Prevents High-Fat Diet Induced Vascular Inflammation, Oxidative Stress, and Pathological Remodeling.},
  author={Jun Chen and Shudong Wang and Manyu Luo and Zhiguo Zhang and Xiaozhen Dai and Maiying Kong and Lu Cai and Yuehui Wang and Bingyin Shi and Yi Tan},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2016},
  volume={153 1},
  pages={124-36}
}
Obesity has become a common public health problem in the world and raises the risk of various cardiovascular diseases. Zinc is essential for multiple organs in terms of normal structure and function. The present study investigated the effects of high fat diet (HFD) induced obesity on the aorta in mice, and evaluated whether it can be affected by zinc deficiency or supplementation. Four-week-old male C57BL/6J mice were fed HFD with varied amounts of zinc (deficiency, adequate and supplementation… CONTINUE READING
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