From the Cover: Interplay Between IFN-γ and IL-6 Impacts the Inflammatory Response and Expression of Interferon-Regulated Genes in Environmental-Induced Autoimmunity.

@article{Cauvi2017FromTC,
  title={From the Cover: Interplay Between IFN-γ and IL-6 Impacts the Inflammatory Response and Expression of Interferon-Regulated Genes in Environmental-Induced Autoimmunity.},
  author={David M Cauvi and Gabrielle Cauvi and Christopher B. Toomey and Eric Jacquinet and Kenneth Michael Pollard},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2017},
  volume={158 1},
  pages={
          227-239
        }
}
IFN-γ has been found to be robustly important to disease pathogenesis in both idiopathic and induced models of murine lupus. In transgenic mice, over production of IFN-γ in the skin results in an inflammatory response and autoimmunity. This suggests that localized exposure to environmental factors that induce autoimmunity may be associated with expression… CONTINUE READING