From the Atmosphere to the Mitochondrion: The Oxygen Cascade

@inproceedings{Biro2013FromTA,
  title={From the Atmosphere to the Mitochondrion: The Oxygen Cascade},
  author={George P. Biro},
  year={2013}
}
This chapter will provide a basic summary of the fundamentals whereby oxygen is delivered from the atmosphere to its ultimate site of utilization, the mitochondria, and the means whereby this delivery is regulated and optimized for efficiency and the “survival” of the organism as a whole. This occurs in four sequential steps comprising 1. convective mass transport exchange of air into and out of the alveolar spaces; 2. diffusive exchange of oxygen and carbon dioxide between alveoli and blood in… 
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11 Citations

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The alveolar-arterial gradient for nitrogen in the steady-state breathing air depends not only on the existence of a distribution of ventilation-perfusion ratios in the lung but also on the presence of a net change in gas volume and is opposite in direction to the direction of net gas volume uptake.
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