From skin microrelief to wrinkles. An area ripe for investigation.

@article{Pirard2003FromSM,
  title={From skin microrelief to wrinkles. An area ripe for investigation.},
  author={G{\'e}rald E. Pi{\'e}rard and Isabelle Uhoda and Claudine Pi{\'e}rard-Franchimont},
  journal={Journal of cosmetic dermatology},
  year={2003},
  volume={2 1},
  pages={21-8}
}
Skin microrelief alters progressively with age. Wrinkles do not result from these changes but are superimposed upon them. Wrinkles result from structural changes in the epidermis, dermis and hypodermis. Four types of wrinkles can be recognized. Type 1 wrinkles are atrophic. Type 2 wrinkles are elastotic. Type 3 wrinkles are expressional. Type 4 wrinkles are gravitational. Each type of wrinkle is characterized by distinct microanatomical changes and each type of wrinkle develops in specific skin… CONTINUE READING