From selenium to selenoproteins: synthesis, identity, and their role in human health.

@article{Papp2007FromST,
  title={From selenium to selenoproteins: synthesis, identity, and their role in human health.},
  author={L. Papp and J. Lu and A. Holmgren and K. Khanna},
  journal={Antioxidants & redox signaling},
  year={2007},
  volume={9 7},
  pages={
          775-806
        }
}
  • L. Papp, J. Lu, +1 author K. Khanna
  • Published 2007
  • Biology, Medicine
  • Antioxidants & redox signaling
  • The requirement of the trace element selenium for life and its beneficial role in human health has been known for several decades. This is attributed to low molecular weight selenium compounds, as well as to its presence within at least 25 proteins, named selenoproteins, in the form of the amino acid selenocysteine (Sec). Incorporation of Sec into selenoproteins employs a unique mechanism that involves decoding of the UGA codon. This process requires multiple features such as the selenocysteine… CONTINUE READING
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