From preeclampsia to renal disease: a role of angiogenic factors and the renin-angiotensin aldosterone system?

@article{Graaf2012FromPT,
  title={From preeclampsia to renal disease: a role of angiogenic factors and the renin-angiotensin aldosterone system?},
  author={Anne Marijn van der Graaf and Tsjitske J. Toering and Marijke M. Faas and A Titia Lely},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2012},
  volume={27 Suppl 3},
  pages={iii51-7}
}
Complicating up to 8% of pregnancies, preeclampsia is the most common glomerular disease worldwide and remains a leading cause of infant and maternal morbidity and mortality. Although the exact pathogenesis of this syndrome of hypertension and proteinuria is still incomplete, a consistent line of evidence has identified an imbalance of proangiogenic and anti-angiogenic proteins as a key factor in the development of preeclampsia. Furthermore, more attention has been recently addressed to the… CONTINUE READING
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