From pre‐cells to Eukarya – a tale of two lipids

@article{Wchtershuser2003FromPT,
  title={From pre‐cells to Eukarya – a tale of two lipids},
  author={G{\"u}nter W{\"a}chtersh{\"a}user},
  journal={Molecular Microbiology},
  year={2003},
  volume={47}
}
A mechanistic hypothesis for the origin of the three domains of life is proposed. A population of evolving pre‐cells is suggested to have had a membrane of a racemate of chiral lipids that continuously underwent spontaneous symmetry breaking by spatial phase segregation into two enantiomerically enriched membrane domains. By frequent pre‐cell fusions and fissions these membrane domains became partitioned between two pre‐cell subpopulations having predominantly one lipid enantiomer or the other… 
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