From pneumonia to DNA: the research career of Oswald T. Avery.

@article{Amsterdamska1993FromPT,
  title={From pneumonia to DNA: the research career of Oswald T. Avery.},
  author={Olga Amsterdamska},
  journal={Historical studies in the physical and biological sciences : HSPS},
  year={1993},
  volume={24 pt 1},
  pages={
          1-40
        }
}
  • O. Amsterdamska
  • Published 1993
  • Business
  • Historical studies in the physical and biological sciences : HSPS
In this article, Amsterdamska uses Avery and his research on bacterial transformation as a case study to assess how different evidential contexts, institutional practices, and ideologies impact the scope and nature of scientific research. 
The chemical characterization of the gene: vicissitudes of evidential assessment.
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A Path to Discovery: The Career of Maclyn McCarty
Maclyn McCarty (1911-2005) was best known for his part in the pioneering discovery that genes are made of DNA.
In search of the best explanation about the nature of the gene: Avery on pneumococcal transformation.
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Adaptation or selection? Old issues and new stakes in the postwar debates over bacterial drug resistance.
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The process of development of the embryo has inspired philosophical speculation since the advent of Western thought. Since the time of Aristotle two antithetical conceptual models have traditionally
Which Half is Mommy?: Tetragametic Chimerism and Trans-Subjectivity
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The process of genetic testing works to publicly legitimate the effectiveness of the test itself while acting to stabilize a narrow and powerful definition of motherhood based on testable biological attributes, and it is argued that the political implications of the established means used to define legitimate mothers extend beyond the trans-genomic quality of chimeric mothers to inform inquiry into reductionist arguments confronted by transgender parents and their children.
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References

SHOWING 1-10 OF 24 REFERENCES
The Rôle of Specific Carbohydrates in Pneumococcus Infection and Immunity
TLDR
Excerpt Mr. President; Fellows of the American College of Physicians: It is a great privilege to be able to express personally his deep sense of appreciation of the distinguish...
Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Inductions of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III
A reprint of Avery, MacLeod, and McCarty's article on the 35th anniversary of its original publication. The introduction is written by Joshua Lederberg.
The Transformation of Pneumococcal Types: I. The Conversion of R Forms of Pneumococcus into S Forms of the Homologous Type [and] II. The Interconvertibility of Type-Specific S Pneumococci
TLDR
The initial findings from experiments meant to follow-up on, and reproduce, and, to an extent, reproduce research on pneumococci in mice which brought about type transformation in vivo that was conducted by English microbiologist Fred Griffith are published.
When does Information become Knowledge ?
By considering a specific example from molecular biology, Dr Wyatt examines the factors that determine the transformation of scientific information into scientific knowledge.
A SELECTIVE MEDIUM FOR B. INFLUENZAE: OLEATE-HEMOGLOBIN AGAR
TLDR
All those who have had experience in the isolation and cultivation of B. influenzae agree that in working with this organism, there are a considerable number of technical difficulties that have been only partly overcome by the methods so far devised.
The Significance of Pneumococcal Types
TLDR
In the course of the examination of sputum from cases of lobar pneumonia, observations have been made on the incidence of the chief types of pneumococci, and the antigens of certain Group IV strains appear to be closely related to that of Type II.
The Professor, the Institute, and DNA
RENA J. DUBOS, The Professor, the Institute, and DNA, New York, Rockefeller University Press, 1976, 8vo, pp. vii, 238, illus., $14.50. Oswald Theodore Avery (1877-1955), nicknamed "The Professor",
Avery in Retrospect
In this response to Vivian Wyatt's article on the cool reception by molecular biologists to Avery, MacLeod, and McCarty's 1944 article, Olby critiqued much of the evidence and many of the primary
THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.
TLDR
Improvements in the methods have resulted in the isolation of the end-products in a form free from nitrogen and of enhanced activity with immune serum, and evidence so far accumulated is believed to favor strongly the view that the polysaccharides isolated are the actual specific substances of Pneumococcus.
THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS
TLDR
Improvements in the methods have resulted in the isolation of the end-products in a form free from nitrogen and of enhanced activity with immune serum, and evidence so far accumulated is believed to favor strongly the view that the polysaccharides isolated are the actual specific substances of Pneumococcus.
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