From oocyte to neuron: Do neurotransmitters function in the same way throughout development?

@article{Buznikov1996FromOT,
  title={From oocyte to neuron: Do neurotransmitters function in the same way throughout development?},
  author={Gennady A. Buznikov and Yuri B. Shmukler and Jean Lauder},
  journal={Cellular and Molecular Neurobiology},
  year={1996},
  volume={16},
  pages={533-559}
}
1. Classical neurotransmitters (such as acetylcholine, biogenic amines, and GABA) are functionally active througout ontogenesis. 2. Based on accumulated evidence, reviewed herein, we present an hypothetical scheme describing developmental changes in this functional activity, from the stage of maturing oocytes through neuronal differentiation. This scheme reflects not only the spatio-temporal sequence of these changes, but also the genesis of neurotransmitter functions, from “protosynapses” in… CONTINUE READING

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