From neutrophil extracellular traps release to thrombosis: an overshooting host‐defense mechanism?

@article{Borissoff2011FromNE,
  title={From neutrophil extracellular traps release to thrombosis: an overshooting host‐defense mechanism?},
  author={Julian Ilcheff Borissoff and Hugo ten Cate},
  journal={Journal of Thrombosis and Haemostasis},
  year={2011},
  volume={9}
}
Innate immunity and blood coagulation are evolutionary entangled in an intricate network of molecular and cellular interactions, thus forming an integral part of the host-defense system [1]. Polymorphonuclear cells, in particular neutrophils, are essential for the primary innate immune response against local and systemic infections or tissue injury [2], but are also major cellularmediators supporting inflammation–coagulation interactions [3]. Upon inflammation, multiple chemotactic stimuli… Expand
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