From meiosis to postmeiotic events: the secrets of histone disappearance.

  title={From meiosis to postmeiotic events: the secrets of histone disappearance.},
  author={Jonathan Gaucher and Nicolas Reynoird and Emilie Montellier and Fayçal Boussouar and Sophie Rousseaux and Saadi Khochbin},
  journal={The FEBS journal},
  volume={277 3},
One of the most obscure phenomena in modern biology is the near genome-wide displacement of histones that occurs during the postmeiotic phases of spermatogenesis in many species. Here we review the literature to show that, during spermatogenic differentiation, three major molecular mechanisms come together to 'prepare' the nucleosomes for facilitated disassembly and histone removal. 

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