From malaria control to eradication: The WHO perspective

  title={From malaria control to eradication: The WHO perspective},
  author={Kamini Nirmala Mendis and Aafje Rietveld and Marian Warsame and Andrea Bosman and Brian Greenwood and Walther H. Wernsdorfer},
  journal={Tropical Medicine \& International Health},
Efforts to control malaria have been boosted in the past few years with increased international funding and greater political commitment. Consequently, the reported malaria burden is being reduced in a number of countries throughout the world, including in some countries in tropical Africa where the burden of malaria is greatest. These achievements have raised new hopes of eradicating malaria. This paper summarizes the outcomes of a World Health Organization’s expert meeting on the feasibility… 

Malaria parasites: elimination is not eradication.

  • V. RobertJ. TrapeC. Rogier
  • Medicine
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2011
In this special issue of Clinical Microbiology and Infection, Brian Greenwood and Geoffrey Targett provide definitions of malaria control, elimination and eradication, before they focus on malaria vaccines and explain why second-generation vaccines are needed even though the first malaria vaccine has not yet been licensed.

Malaria: Control, Elimination, and Eradication

The current state of malaria control and elimination and the need for an multistrategic integrated approach in order to achieve malaria eradication if the challenges faced by elimination are addressed are addressed.

Integrated approaches to malaria control - addressing new challenges to malaria research

Canada’s International Research Development Centre, IDRC, is currently supporting the formation and consolidation of multi-national, multi-disciplinary research consortia in high-transmission and high-burden countries of Sub-Saharan Africa.


RDT showed to be a good and reliable source of parasite DNA, useful for malaria case detection, molecular surveillance and RDT quality control and performed well in the IMCI algorithm with equally high adherence among children under five as compared with other age groups.

Antimalarial Drugs and the Control and Elimination of Malaria

To reduce the probability of resistance, antimalarials should be used in quality-assured fixed-dose combinations and treatment doses need to be optimised on the basis of pharmacokinetic assessments conducted within therapeutic efficacy studies in each key target population.

Country-Owned, Country-Driven: Perspectives from the World Health Organization on Malaria Elimination.

This chapter recounts the history of malaria eradication and elimination efforts throughout the world and focuses on the current status of country-led and country-driven malaria elimination programs, along with the technical strategies recommended by the World Health Organization for achievement of malaria elimination.

A framework for assessing the feasibility of malaria elimination

A quantitative feasibility assessment that balances the epidemiological situation in a region, the strength of the public health system, the resource constraints, and the status of malaria control in neighboring areas can serve as the basis for robust, long-term strategic planning.

History of malaria research and its contribution to the malaria control success in Suriname: a review

Effective preventive measures and adequate therapeutic options are on their own not enough to control, let alone eliminate malaria, but practical initiatives of combined efforts between neighbouring countries must be scaled up in order to effectively attack these specific areas.



Malaria eradication back on the table.

After a lapse of almost 40 years, malaria eradication is back on the global health agenda and key organizations are starting to debate the pros and cons of redefining eradication as an explicit goal of malaria control efforts.

A new global malaria eradication strategy

The "Roll Back Malaria" Campaign

The World Health Organization's new Director General, Gro Harlem Brundtland, is proposing an international partnership working toward common objectives through an agreed strategy, made up of organizations dedicated to research and disease control in the public and private sectors, together with national governments, international organizations, and development banks.

Roll back malaria is unarguably both necessary and possible.

Some of the challenges in the task of reducing incidence of malaria are discussed, it is emphasized that such difficulties can be tackled by applying science human and financial resources and effective organization.

Global malaria control and elimination: report of a technical review.

This paper outlined the current global malaria situation and control progress, and proposed the strategy and prospect of global malaria control and elimination in the future based on the theory of transmission dynamics of malaria.

Estimated global resources needed to attain international malaria control goals.

Estimates of the scale and scope of resources required to scale up malaria control to reach international goals can help donors to collaborate towards meeting a global benchmark and targeting funding to countries in greatest need.

Impact of chloroquine resistance on malaria mortality.

The entomological inoculation rate and Plasmodium falciparum infection in African children

Strong evidence is found that heterogeneous biting or heterogeneous susceptibility to infection are important and pervasive factors determining the prevalence of infection: 20% of people receive 80% of all infections.

Short report: entomologic inoculation rates and Plasmodium falciparum malaria prevalence in Africa.

It is shown convincingly that substantial reductions in malaria prevalence are likely to be achieved only when EIRs are reduced to levels less than 1 infective bite per person per year, and highlights that the EIR is a more direct measure of transmission intensity than traditional measures of malaria prevalence or hospital-based measures of infection or disease incidence.

Revisiting the Basic Reproductive Number for Malaria and Its Implications for Malaria Control

This work estimates R 0 in a novel way for 121 African populations, and thereby increases the number of R 0 estimates for malaria by an order of magnitude, which strongly supports the long-held notion that malaria control presents variable challenges across its transmission spectrum.