From macroscopic measurements to microscopic mechanisms of protein aggregation.

@article{Cohen2012FromMM,
  title={From macroscopic measurements to microscopic mechanisms of protein aggregation.},
  author={Samuel I. A. Cohen and Michele Vendruscolo and Christopher M. Dobson and Tuomas P. J. Knowles},
  journal={Journal of molecular biology},
  year={2012},
  volume={421 2-3},
  pages={160-71}
}
The ability to relate bulk experimental measurements of amyloid formation to the microscopic assembly processes that underlie protein aggregation is critical in order to achieve a quantitative understanding of this complex phenomenon. In this review, we focus on the insights from classical and modern theories of linear growth phenomena and discuss how… CONTINUE READING