From known knowns to known unknowns: predicting in vivo drug metabolites.

Abstract

'It is better to be useful than perfect'. This review attempts to critically cover and assess the currently available approaches and tools to answer the crucial question: Is it possible (and if it is, to what extent is it possible) to predict in vivo metabolites and their abundances on the basis of in vitro and preclinical animal studies? In preclinical… (More)
DOI: 10.4155/bio.09.32

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Cite this paper

@article{Pelkonen2009FromKK, title={From known knowns to known unknowns: predicting in vivo drug metabolites.}, author={Olavi Pelkonen and Ari Tolonen and Timo Korjamo and Miia Turpeinen and Hannu Raunio}, journal={Bioanalysis}, year={2009}, volume={1 2}, pages={393-414} }