From hepatitis C virus immunoproteomics to rheumatology via cross-reactivity in one table.

  title={From hepatitis C virus immunoproteomics to rheumatology via cross-reactivity in one table.},
  author={Darja Kanduc},
  journal={Current Opinion in Rheumatology},
  • D. Kanduc
  • Published 1 September 2019
  • Biology, Medicine
  • Current Opinion in Rheumatology
PURPOSE OF REVIEW To give an overview of molecular and immunologic data that link hepatitis C virus (HCV) infection to rheumatic diseases in the human host. RECENT FINDINGS A high level of peptide sharing exists between immunopositive HCV epitopes and human proteins that, when altered, associate with rheumatic manifestations. SUMMARY The findings suggest the involvement of HCV infection in the induction of most rheumatic diseases via a mechanism of autoimmune cross-reactivity. 

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