From hemangioblast to hematopoietic stem cell: an endothelial connection?

  title={From hemangioblast to hematopoietic stem cell: an endothelial connection?},
  author={Thierry Jaffredo and Wade T. Nottingham and Kate Liddiard and Karine Boll{\'e}rot and Claire Pouget and Marella Ftr de Bruijn},
  journal={Experimental hematology},
  volume={33 9},
The developmental origin of hematopoietic stem cells has been the subject of much research. Now that the developmental link between the hematopoietic system and the vasculature has been well established, questions remain regarding the precise cellular origin of definitive hematopoietic cells and at what point they branch off from the endothelial lineage. Do they emerge directly from a hemangioblast-type cell, similar to what is proposed for primitive yolk sac hematopoiesis, or are they… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 64 extracted citations

Similar Papers

Loading similar papers…