From blood oxygenation level dependent (BOLD) signals to brain temperature maps.

@article{Sotero2011FromBO,
  title={From blood oxygenation level dependent (BOLD) signals to brain temperature maps.},
  author={Roberto C. Sotero and Yasser Iturria-Medina},
  journal={Bulletin of mathematical biology},
  year={2011},
  volume={73 11},
  pages={
          2731-47
        }
}
A theoretical framework is presented for converting Blood Oxygenation Level Dependent (BOLD) images to brain temperature maps, based on the idea that disproportional local changes in cerebral blood flow (CBF) as compared with cerebral metabolic rate of oxygen consumption (CMRO₂) during functional brain activity, lead to both brain temperature changes and the BOLD effect. Using an oxygen limitation model and a BOLD signal model, we obtain a transcendental equation relating CBF and CMRO₂ changes… CONTINUE READING
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