From behavior to development: genes for sexual behavior define the neuronal sexual switch in Drosophila

  title={From behavior to development: genes for sexual behavior define the neuronal sexual switch in Drosophila},
  author={D. Yamamoto and K. Fujitani and K. Usui and H. Ito and Y. Nakano},
  journal={Mechanisms of Development},
  • D. Yamamoto, K. Fujitani, +2 authors Y. Nakano
  • Published 1998
  • Medicine, Biology
  • Mechanisms of Development
  • The isolation and analysis of Drosophila mutants with altered sexual orientation lead to the identification of novel branches in the sex-determination cascade which govern the sexually dimorphic development of the nervous system. One such example is the fruitless (fru) gene, the mutation of which induces male-to-male courtship and malformation of a male-specific muscle, the muscle of Lawrence (MOL). Since the MOL is formed in wild-type flies when the innervating nerve is male, regardless of the… CONTINUE READING
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