From bacterial killing to immune modulation: Recent insights into the functions of lysozyme

@inproceedings{Ragland2017FromBK,
  title={From bacterial killing to immune modulation: Recent insights into the functions of lysozyme},
  author={Stephanie A Ragland and Alison K Criss},
  booktitle={PLoS pathogens},
  year={2017}
}
Lysozyme is a cornerstone of innate immunity. The canonical mechanism for bacterial killing by lysozyme occurs through the hydrolysis of cell wall peptidoglycan (PG). Conventional type (c-type) lysozymes are also highly cationic and can kill certain bacteria independently of PG hydrolytic activity. Reflecting the ongoing arms race between host and invading microorganisms, both gram-positive and gram-negative bacteria have evolved mechanisms to thwart killing by lysozyme. In addition to its… CONTINUE READING
Highly Cited
This paper has 24 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 30 times. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Rip 2 Is Required for Nod 2Mediated Lysozyme Sorting in Paneth Cells

H Wang, X Zhang, +3 authors B Zeng
J Immunol • 2017

Similar Papers

Loading similar papers…