From atomic to mesoscopic descriptions of the internal dynamics of DNA.

@article{Bruant1999FromAT,
  title={From atomic to mesoscopic descriptions of the internal dynamics of DNA.},
  author={N. Bruant and Delphine Flatters and Richard Lavery and Daniel Genest},
  journal={Biophysical journal},
  year={1999},
  volume={77 5},
  pages={2366-76}
}
An analysis of four 1-ns molecular dynamics trajectories for two different 15-bp oligonucleotides is presented. Our aim is to show which groups of atoms can be treated as rigid bodies within a bead representation of DNA, independently of the base sequence and for any conformations belonging to the A/B family. Five models with moderate intragroup deformations are proposed in which the groups are formed of atoms belonging to a single nucleotide or to a complementary nucleotide pair. The influence… CONTINUE READING

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