From Stem Cell to Embryo without Centrioles

@inproceedings{Stevens2007FromSC,
  title={From Stem Cell to Embryo without Centrioles},
  author={Naomi R. Stevens and Alexandre A. S. F. Raposo and Renata Basto and Daniel St Johnston and Jordan W Raff},
  booktitle={Current Biology},
  year={2007}
}
Centrosome asymmetry plays a key role in ensuring the asymmetric division of Drosophila neural stem cells (neuroblasts [NBs]) and male germline stem cells (GSCs) [1-3]. In both cases, one centrosome is anchored close to a specific cortical region during interphase, thus defining the orientation of the spindle during the ensuing mitosis. To test whether asymmetric centrosome behavior is a general feature of stem cells, we have studied female GSCs, which divide asymmetrically, producing another… CONTINUE READING
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