From Human Cytogenetics to Human Chromosomics

  title={From Human Cytogenetics to Human Chromosomics},
  author={Thomas Liehr},
  journal={International Journal of Molecular Sciences},
  • T. Liehr
  • Published 1 February 2019
  • Biology, Medicine
  • International Journal of Molecular Sciences
Background: The concept of “chromosomics” was introduced by Prof. Uwe Claussen in 2005. Herein, the growing insights into human chromosome structure finally lead to a “chromosomic view” of the three-dimensional constitution and plasticity of genes in interphase nuclei are discussed. This review is dedicated to the memory of Prof. Uwe Claussen (30 April 1945–20 July 2008). Recent findings: Chromosomics is the study of chromosomes, their three-dimensional positioning in the interphase nucleus… 

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