From Exotic Spice to Modern Drug?

@article{Singh2007FromES,
  title={From Exotic Spice to Modern Drug?},
  author={Seema Singh},
  journal={Cell},
  year={2007},
  volume={130},
  pages={765-768}
}

Figures from this paper

Plant-derived natural products as leads for drug discovery
In this chapter, some successful drugs derived from plant secondary metabolites in their original or modified forms, and other substances, currently under clinical trial as drug candidates, as well
Contribution à l'étude de l’effet hépato-épuratif de curcuma (Curcuma Longa)
R3UNIVERSITE KASDI MERBAH OUARGLA Faculte des Sciences de la Nature et de la Vie Departement des Sciences Biologiques
Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review
TLDR
Turmeric possesses several biological activities including anti-inflammatory, antioxidant, anticancer, antimutagenic, antimicrobial, antiobesity, hypolipidemic, cardioprotective, and neuroprotective effects, which make it an important option for further clinical research.
Curcumin, a component of turmeric: From farm to pharmacy
TLDR
Evidence for the pharmaceutical uses of curcumin for various diseases is provided, including cancer, pulmonary diseases, neurological diseases, liver diseases, metabolic diseases, autoimmune diseases, cardiovascular diseases, and numerous other chronic diseases.
Curcumin and Its Role in Chronic Diseases.
TLDR
With much more scope to be investigated and understood, curcumin becomes one of the very few inexpensive botanical molecules with potent therapeutic abilities.
Recent developments in anti‐inflammatory natural products
TLDR
The present review article describes anti‐inflammatory natural products derived from plants and marine sources reported during last decade, which belong to different chemical classes such as alkaloids, steroids, terpenoids, polyphenolics, phenylpropanoids, fatty acids and lipids, and various miscellaneous compounds.
Neem (Azadirachta indica): An indian traditional panacea with modern molecular basis.
Curcumin (Turmeric) and cancer.
TLDR
When its advantages in terms of toxicity, cost and availability as well as the favorable results achieved in laboratory studies are considered, it would not be wrong to say that curcumin is a substance worth being studied.
Turmeric: An Overview of Potential Health Benefits
TLDR
Curcumin, an orange-yellow powder that has potent anti-inflammatory and antioxidant properties, may contribute to curcumin’s potential to prevent such conditions as cancer, Alzheimer disease, heart disease, and arthritis, to name a few.
REVERSE PHARMACOLOGY: A NEW APPROACH TO DRUG DEVELOPMENT
TLDR
R reverse pharmacology also known as target base drug discovery (TDD) is now becoming a popular option in the field of drug discovery where a hypothesis is first made that modulation of the activity of a specific protein target will have beneficial therapeutic effects.
...
...