From ‘protein’ to the beginnings of clinical proteomics

@article{Perrett2007FromT,
  title={From ‘protein’ to the beginnings of clinical proteomics},
  author={D. Perrett},
  journal={PROTEOMICS – Clinical Applications},
  year={2007},
  volume={1}
}
  • D. Perrett
  • Published 2007
  • Biology, Medicine
  • PROTEOMICS – Clinical Applications
  • It has taken over 200 years to move from the view that there was a single unique ‘protein’ to our present understanding that there may be over a million proteins in the human body. This review details the technological developments that led to this increase in knowledge especially in the area of clinical biochemistry. Simple techniques such as total protein assays allowed the quantitation of the amounts of protein in blood plasma and serum. These techniques were then linked to simple… CONTINUE READING
    29 Citations

    Topics from this paper

    High-throughput protein analysis using mass spectrometry-based methods
    • 5
    • PDF
    On the binding affinity of macromolecular interactions: daring to ask why proteins interact
    • 269
    • PDF
    A brief history of prions.
    • 30
    • PDF
    Network-based inference of protein function and disease-gene association
    • Highly Influenced
    • PDF

    References

    SHOWING 1-10 OF 112 REFERENCES
    The Human Plasma Proteome
    • 3,029
    • PDF
    Chromatographic and Electrophoretic Techniques
    • 1,317
    • PDF
    Electrophoresis: the march of pennies, the march of dimes.
    • 81
    Determination of serum proteins by means of the biuret reaction.
    • 13,315
    • PDF
    Zone electrophoresis in starch gels and its application to studies of serum proteins.
    • O. Smithies
    • Chemistry, Medicine
    • Advances in protein chemistry
    • 1959
    • 550
    Joachim kohn (1912-1987) and the origin of cellulose acetate electrophoresis.
    • 13
    • PDF