Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals.

@article{Park2006FrodoLD,
  title={Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals.},
  author={Jae-il Park and Hong Ji and Sohee Jun and Dongmin Gu and Hiroki Hikasa and Lei Li and Sergei Y Sokol and Pierre D. McCrea},
  journal={Developmental cell},
  year={2006},
  volume={11 5},
  pages={683-95}
}
p120-catenin is an Arm repeat protein that interacts with varied components such as cadherin, small G proteins, kinases, and the Kaiso transcriptional repressor. Despite recent advances in understanding the roles that p120-catenin and Kaiso play in downstream modulation of Wnt/beta-catenin signaling, the identity of the upstream regulators of the p120-catenin/Kaiso pathway have remained unclear. Here, we find that p120-catenin binds Frodo, which itself interacts with the Wnt pathway protein… CONTINUE READING

From This Paper

Topics from this paper.
46 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

Similar Papers

Loading similar papers…