Frequent rearrangements of chromosomes 1, 7, and 8 in primary liver cancer.

@article{Parada1998FrequentRO,
  title={Frequent rearrangements of chromosomes 1, 7, and 8 in primary liver cancer.},
  author={Luis Antonio Parada and Magnus Hall{\'e}n and Karl-G. Tranberg and Inga H{\"a}gerstrand and Lennart Bondeson and Felix Mitelman and Bertil Johansson},
  journal={Genes, chromosomes & cancer},
  year={1998},
  volume={23 1},
  pages={26-35}
}
Fifteen primary liver carcinomas (PLCs), including 12 hepatocellular carcinomas and three cholangiocellular carcinomas, were investigated cytogenetically after short-term culture. Ten tumors displayed clonal chromosomal abnormalities, whereas only normal karyotypes were detected in four cases, and one sample failed to grow in vitro. Structural rearrangements most often involved chromosomes 1, 7, and 8 and chromosome bands 1p36, 1q25, 3q10, 5q13, 6p10, 7p15, 7q22, 7q32, 8q10, 8q13, 14q10, and… CONTINUE READING