Frequent loss of the long arm of chromosome 18 in esophageal squamous cell carcinoma.

@article{Ando2007FrequentLO,
  title={Frequent loss of the long arm of chromosome 18 in esophageal squamous cell carcinoma.},
  author={Takuya Ando and Hideyuki Ishiguro and Masahiro Kimura and Akira Mitsui and Yoichiro Mori and Nobuyoshi Sugito and Keisuke Tomoda and R. De Mori and Koshiro Harada and Takeyasu Katada and Ryoichi Ogawa and Yoshitaka Fujii and Yoshiyuki Kuwabara},
  journal={Oncology reports},
  year={2007},
  volume={17 5},
  pages={
          1005-11
        }
}
Esophageal squamous cell carcinoma (ESCC) is one of the most common and deadly cancers in Japan. In this study we performed fluorescent in situ hybridization (FISH) and loss of heterozygosity (LOH) analysis for chromosome 18q in ESCC cells to investigate allelic imbalance of chromosome 18q in ESCC. In the FISH analysis, only one signal for chromosome 18q was detected in TE-1 esophageal cancer cells, whereas two signals were detected in TE-2 cells. Two of five resected ESCC samples from patients… CONTINUE READING

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