Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Tampere CLL Group.

@article{Karhu1997FrequentLO,
  title={Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Tampere CLL Group.},
  author={Ritva Karhu and Sakari Knuutila and Olli Kallioniemi and S Siltonen and R. A. T. Aine and Leena Vilpo and Juhani A. Vilpo},
  journal={Genes, chromosomes & cancer},
  year={1997},
  volume={19 4},
  pages={286-90}
}
The genetic basis and molecular pathogenesis of chronic lymphocytic leukemia (CLL) and the molecular mechanisms responsible for its progression remain poorly understood. Here, karyotyping techniques specifically optimized for CLL, comparative genomic hybridization (CGH), and fluorescence in situ hybridization were used to search for CLL-specific genetic… CONTINUE READING