Frequent atrophic groups with mixed-type myofibers is distinctive to motor neuron syndromes.

@article{Baloh2007FrequentAG,
  title={Frequent atrophic groups with mixed-type myofibers is distinctive to motor neuron syndromes.},
  author={Robert H Baloh and Wojtek P Rakowicz and Robert Andrew Gardner and Alan Pestronk},
  journal={Muscle & nerve},
  year={2007},
  volume={36 1},
  pages={107-10}
}
This study was performed to determine whether there are distinctive features to the pattern of muscle denervation in motor neuron disease. We first compared muscle biopsies from patients with amyotrophic lateral sclerosis (ALS) or Kennedy's disease with other causes of denervation. Groups of atrophic muscle fibers, with individual groups containing both fiber types I and II, occurred frequently in motor neuron disease but not other causes of denervation. We then identified 11 additional muscle… CONTINUE READING